Thermo Fisher Scientific GeneBLAzer AVPR1a-NFAT-bla CHO-K1 Cells
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| 카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
| K1715 | - | Thermo Fisher Scientific K1715 GeneBLAzer AVPR1a-NFAT-bla CHO-K1 Cells Each pk | 재고문의 | pk | 0원 | - | 0원 | |
다른 상품 둘러보기
Thermo Scientific™
GeneBLAzer™ AVPR1a-NFAT-bla CHO-K1 Cells
GeneBLAzer™ AVPR1a-NFAT-bla CHO-K1 cells contain the human Arginine Vasopressin Receptor 1a (AVPR1a) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell자세히 알아보기
GeneBLAzer™ AVPR1a-NFAT-bla CHO-K1 cells contain the human Arginine Vasopressin Receptor 1a (AVPR1a) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ AVPR1a-NFAT-bla CHO-K1 cells are functionally validated for Z` and EC50 concentrations of Vasopressin. In addition, GeneBLAzer™ AVPR1a-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The family of receptors that recognize vasopressin and oxytocin consists of four members: vasopressin receptors 1a (AVPR1a), 1b (AVPR1b), and 2 (AVPR2), and the oxytocin (OT) receptor. AVPR1a, AVPR1b, and the OT receptor couple to the Gq/G11 class of G proteins and trigger the release of intracellular calcium when stimulated. AVPR2 receptors couple to Gs proteins and activate adenyl cyclase. All three AVPR receptors have high affinity for their endogenous ligand, vasopressin, but AVPR1b has less affinity for oxytocin than does AVPR1a or AVPR2. The hormones vasopressin and oxytocin are synthesized in the hypothalamus. Oxytocin causes contractions in the uterus during childbirth. The main functions of arginine vasopressin (AVP) are reabsorption of water by the kidneys and contraction of smooth muscle in arteries. This system may also play a role in memory and learning.
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사양
등록 번호NM_000706.3
어세이 입력Cell-based beta lactamase reporter gene
셀 상태Dividing Cells
검출 방법Fluorescence
용도(애플리케이션)FRET
유전자 기호AVPR1a
개체군 상태Single Cell Clone Origin
제품라인GeneBLAzer™
수량2 x 106 cells
리포터 유전자BLA (Beta-Lactamase)
타겟 입력AVPR1A
세포주CHO-K1
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit SizeEach
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