Thermo Fisher Scientific alpha Internexin Polyclonal Antibody
다양한 응용(WB, IHC, ICC/IF)에 적합한 alpha Internexin 폴리클로날 항체로, 마우스 및 랫트 반응성이 우수합니다. 항원 친화 크로마토그래피로 정제되었으며, 신경세포 발달 및 분화 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of mouse alpha Internexin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.24 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792925 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (83%).
- Positive Control: mouse brain, rat brain.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to, but distinct from, the neurofilament triplet proteins (NF-L, NF-M, NF-H), sharing similar sequence motifs and intron organization.
Many mature neurons contain alpha-Internexin in addition to NF-L, NF-M, and NF-H, while in some it is the only neurofilament subunit expressed.
Antibodies to alpha-Internexin serve as unique probes to study neuronal types and processes in tissue sections and cultures.
Its early developmental expression makes it a useful marker for neuronal progenitor cells and cells committed to the neuronal lineage.
Potential applications include studies of brain development and neuro-oncology.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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