Thermo Fisher Scientific TSC22D1 Polyclonal Antibody
TSC22D1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 Affinity chromatography 정제 및 PBS/glycerol buffer 보존. 세포 성장과 분화 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TSC22D1 (Accession Q15714), corresponding to amino acid residues P1033–A1073 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900714 |
Product Specific Information
Antibody detects endogenous levels of total TSC22D1.
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the large family of early response genes. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter. TSC22 is an intracellular protein found in the cytoplasm or nucleus and regulates cell growth, differentiation, and apoptosis. It modulates the transcriptional activity of Smad3 and Smad4 and is ubiquitously expressed in both fetal and adult tissues, including aortic endothelial cells. Expression is induced by cytokines such as TGFB. These proteins may serve as potential therapeutic targets for leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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