Thermo Fisher Scientific Phospho-Kidins220 (ARMS) (Ser919) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phospho-Kidins220 (Ser919). Validated for Western blot. Useful for studying neuronal signaling and neurodegenerative disease mechanisms. Supplied as liquid, 1 mg/mL, stored at 4°C short term or -20°C long term.
- 카탈로그번호
- RA19020-100UL
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Residues 907–923 [RQMQRTITRQMpS919FDLTK] of the human 220 kDa Kidins220 protein (serine 919 phosphorylated, pS919) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system, where it regulates neuronal cell survival, differentiation into axons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, acting as a scaffold that mediates crosstalk between the neurotrophin pathway and other intracellular signaling cascades. Aberrant expression is associated with neuropsychiatric and neurodegenerative disorders, including Alzheimer’s disease. Mutations in this gene can cause a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus, and obesity. Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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