Thermo Fisher Scientific Human TEM8 Synthetic Peptide
인간 TEM8 단백질의 중심부 13개 아미노산 서열을 기반으로 한 합성 펩타이드. TEM8 항체의 차단 실험에 사용 가능. 정제된 액상 형태로 PBS 버퍼에 보존. 인간 반응성, 연구용 전용 시약.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the center of human TEM8.
PEP-0135 can be used as a blocking peptide with polyclonal antibody PA5-20016.
Target Information
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein also serves as a receptor for Bacillus anthracis toxin, the causative agent of anthrax. The binding of the protective antigen (PA) component to this receptor mediates delivery of toxin components to the cytosol of cells. Once inside the cell, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Three alternatively spliced variants encoding different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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