Thermo Fisher Scientific H3K14me3 Polyclonal Antibody
H3K14me3 변형 히스톤 H3를 인식하는 Rabbit Polyclonal 항체. Western blot, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human Histone H3 (NP_003520.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.95 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806458 |
Product Specific Information
- Positive Samples: HeLa, H3 protein
- Cellular Location: Chromosome, Nucleus
- Immunogen Sequence: KSTGGKAPRKQ
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. Along with four core histone proteins, it binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can alter chromatin structure or facilitate transcription factor binding. The N-terminal tail of histone H3 can undergo modifications such as methylation, acetylation, and phosphorylation, which influence various cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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