Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI1E12), TrueMAB
HNRNPM 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합합니다. E. coli에서 생산된 인간 HNRNPM(aa 1-261) 재조합 단백질을 면역원으로 사용했으며, 액상 형태로 제공됩니다. -20°C에서 보관하며 반복 동결·해동은 피해야 합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–261 of human HNRNPM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogeneous nuclear ribonucleoproteins (hnRNPs), play an important role in transcript-specific packaging and alternative splicing of pre-mRNAs.
The M1–M4 proteins form a cluster of abundant hnRNPs that bind pre-mRNA in vivo and poly(G)/poly(U) RNA homopolymers in vitro.
These M proteins belong to the ribonucleoprotein consensus sequence family of RNA-binding proteins, showing similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae.
They also contain a methionine/arginine-rich hexapeptide repeat motif (MR repeat) resembling a repeat in the 64 kDa subunit of cleavage stimulation factor, involved in 3'-end maturation of pre-mRNAs.
Immunologically related M proteins exist in eukaryotes ranging from human to yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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