Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI3F3), TrueMAB
Human HNRNPM 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot과 IHC(P) 실험에 적합함. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 저장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–261 of human HNRNPM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogeneous nuclear ribonucleoproteins (hnRNPs), play an important role in transcript-specific packaging and alternative splicing of pre-mRNAs. The M1–M4 proteins form a cluster of four abundant hnRNPs that bind pre-mRNA in vivo and interact strongly with poly(G) and poly(U) RNA homopolymers in vitro. These M proteins belong to the ribonucleoprotein consensus sequence family of RNA-binding proteins, showing similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. They possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif), resembling a repeat found in the 64 kDa subunit of cleavage stimulation factor involved in 3'-end maturation of pre-mRNAs. Proteins immunologically related to M exist across diverse eukaryotes from humans to yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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