Thermo Fisher Scientific Nkx6.1 Polyclonal Antibody
Thermo Fisher Scientific의 Nkx6.1 Polyclonal Antibody는 인간, 생쥐, 랫트에서 반응하며, 다양한 면역 분석(WB, IHC, ICC 등)에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 액상 형태이며 장기 보관 시 -20°C에서 안정적 저장 가능.
- 카탈로그번호
- PA523070
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| In vitro Assay (IV) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal region of the human Nkx6.1 protein (within residues 50–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11151940 |
Product Specific Information
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Target Information
NKX6.1 is a bi-functional transcription factor active in both the central nervous system and pancreas. It regulates gene expression and repression, contributing to the development of motoneurons, oligodendrocytes, and insulin-secreting beta cells. NKX6.1 interacts with Pax6 and Pdx-1 near the homeobox DNA-binding domain and is a promising target for diabetes and neurological disease research.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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