Thermo Fisher Scientific SF3B1 Polyclonal Antibody
Human SF3B1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체. 비결합형 액상 형태로 안정적이며, 연구용으로만 사용 가능.
- 카탈로그번호
- PA583997
- 판매단위
- pk
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Thermo Fisher Scientific SF3B1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SF3B1. Recombinant protein control fragment (Product #RP-101202). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791149 |
Product Specific Information
Immunogen sequence:
LDSTGYYDQE IYGGSDSRFA GYVTSIAATE LEDDDDDYSS STSLLGQKKP GYHAPVALLN DIPQSTEQYD PFAEHRPPKI ADRED
Target Information
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex. The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron’s branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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