Thermo Fisher Scientific TIS11D Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 TIS11D(ZFP36L2) 단백질을 인식합니다. Western blot 및 IHC에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 및 sucrose buffer에 0.5 mg/mL 농도로 제공되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific TIS11D Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human ZFP36L2 (aa 36–85) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609141 |
Product Specific Information
- Peptide sequence: VGTPVAAAPS SGFAPGFLRR HSASNLHALA HPAPSPGSCS PKFPGAANGS
- Sequence homology: Cow 92%, Guinea Pig 85%, Mouse 84%, Rat 84%
Target Information
TIS11D, also known as ZFP36L2 (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2, or RNF162C, is a 494 amino acid nuclear protein containing two CSH1-type zinc fingers.
It belongs to the TIS11 family of early response proteins and functions as a nuclear transcription factor that binds to 5’ UUAUUUAUUU-3’ core RNA sequences, potentially regulating growth factor-induced cellular responses.
The gene encoding TIS11D maps to human chromosome 2, which contains over 1,400 genes and represents approximately 8% of the human genome.
Harlequin ichthyosis, a rare skin deformity, is associated with ABCA12 gene mutations, while lipid metabolic disorder sitosterolemia relates to ABCG5 and ABCG8 gene defects.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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