Thermo Fisher Scientific ING3 Polyclonal Antibody
ING3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 단백질에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ING3 Polyclonal Antibody
Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human ING3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576934 |
Product Specific Information
- Peptide sequence: LSSGTGAGAI TMAAAQAVQA TAQMKEGRRT SSLKASYEAF KNNDFQLGKE
- Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 75%; Zebrafish: 92%
Target Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, a common motif in chromatin remodeling proteins. It can activate p53 trans-activated promoters, including p21/waf1 and bax. Overexpression has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression have been observed in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.