Thermo Fisher Scientific TWEAK Chimeric Recombinant Rabbit Monoclonal Antibody (MTW-1)
마우스 TWEAK에 특이적인 재조합 래빗 단클론 항체로 다양한 면역분석(ICC/IF, Flow, IA)에 사용 가능. HEK293 세포 발현, Protein A 정제, 액상 형태로 제공. 장기 보관 시 -20°C에서 냉동 보관 권장. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
- Publications: -
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
- Publications: -
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MTW-1 |
| Immunogen | CD8-mTWEAK (human CD8α extracellular region fused to murine TWEAK) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3074672 |
Product Specific Information
Specificity: This antibody is specific for murine TWEAK. It does not react with TNF-alpha, FasL, or TRAIL.
Target Information
TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF superfamily (TNFSF). It is a type II transmembrane protein, though a smaller active soluble form can be generated by cleavage near the membrane. TWEAK is involved in cell growth, angiogenesis, induction of inflammatory cytokines, and apoptosis. It signals via TweakR/Fn14, similar to other TNFSF members that bind receptors lacking death domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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