Thermo Fisher Scientific PCSK6 Polyclonal Antibody
PCSK6 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. IHC(P) 및 ELISA에 사용 가능하며, 인간과 토끼에 반응. 항원 친화 크로마토그래피로 정제, PBS 버퍼에 0.1% sodium azide 함유. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 20 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human PACE4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550428 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Rabbit (100%); Gibbon, Monkey (94%); Marmoset, Mouse, Rat, Bovine, Dog, Elephant, Panda, Horse, Pig, Opossum (88%). - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. Members of this family process latent precursor proteins into their biologically active forms. This encoded protein is a calcium-dependent serine endoprotease that cleaves precursor proteins at paired basic amino acid processing sites. Known substrates include transforming growth factor beta-related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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