Thermo Fisher Scientific KAT II Polyclonal Antibody
KAT II 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, ELISA, IP에 사용 가능. 마우스 반응성, 비결합형 액상 항체이며 친화 크로마토그래피로 정제됨. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KAT II affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of mouse KAT II. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 50% glycerol, 1mg/mL BSA, 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis was used to suggest cross-reactivity with human, rat, and mouse based on 100% sequence homology. Cross-reactivity with KAT II from other sources has not been determined.
Target Information
This gene encodes a protein highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities:
- Transamination of alpha-aminoadipic acid, a final step in the saccharopine pathway for L-lysine catabolism.
- Transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid, which has neuroprotective properties.
Two alternative transcripts encoding the same isoform have been identified; however, additional alternative transcripts and isoforms may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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