Thermo Fisher Scientific Phospho-EDC3 (Ser161) Polyclonal Antibody
Phospho-EDC3 (Ser161) 폴리클로날 항체로, 마우스 EDC3 단백질의 인산화된 S161 부위를 특이적으로 인식합니다. Western blot, ELISA, IP에 적합하며, 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EDC3 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic phospho-peptide surrounding the pS161 site of mouse EDC3. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Anti-EDC3 pS161 is specific for phospho S161 mouse EDC3.
A BLAST analysis suggests cross-reactivity with rabbit, pig, monkey, bovine, rat, mouse, and bat based on 100% sequence homology.
Cross-reactivity with EDC3 pS161 from other sources has not been determined.
Target Information
This gene encodes a protein important in mRNA degradation.
The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5′ to 3′ mRNA decay pathway.
Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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