Thermo Fisher Scientific Phospho-EDC3 (Ser161) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

Anti-EDC3 pS161 is specific for phospho S161 mouse EDC3.
A BLAST analysis suggests cross-reactivity with rabbit, pig, monkey, bovine, rat, mouse, and bat based on 100% sequence homology.
Cross-reactivity with EDC3 pS161 from other sources has not been determined.

Target Information

This gene encodes a protein important in mRNA degradation.
The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5′ to 3′ mRNA decay pathway.
Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.