Thermo Fisher Scientific Glutamine Synthetase Polyclonal Antibody
Glutamine Synthetase 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용 가능. Bovine, Human, Mouse, Rat 종에 반응하며, 비결합형 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Glutamine Synthetase Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | View publication |
| Immunocytochemistry (ICC/IF) | 1:500–1:1,000 | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Glutamine Synthetase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2263362 |
Product Specific Information
Suggested positive control: antigen standard for GLUL (transient overexpression lysate), retinal Müller cells.
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism. Due to its multiple functions and importance in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation and is decreased in the cerebral cortex of brains affected by Alzheimer’s disease, particularly near senile plaques. It is also reduced under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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