Thermo Fisher Scientific NR5A1 Polyclonal Antibody
Human NR5A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 7 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 0.1% sodium azide 함유. 내분비계 기관 발달 연구에 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific NR5A1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from ligand-binding domain of human NR5A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551375 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Mouse, Rat, Hamster, Elephant, Dog, Horse, Pig (94%).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1, AF2), common to many nuclear steroid receptors, necessary for interaction with other nuclear receptors and coactivators/corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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