Thermo Fisher Scientific NR5A1 Polyclonal Antibody
Human NR5A1(SF-1) 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50 희석 권장. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide 포함. 내분비계 기관 발달 연구에 적합.
- 카탈로그번호
- PA534014
- 판매단위
- pk
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human NR5A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551374 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%); Rat (88%); Mouse, Dog, Bovine, Elephant, Panda, Horse, Pig (81%).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system.
SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2), which are necessary for interaction with other nuclear receptors and coactivators/corepressors such as SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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