Thermo Fisher Scientific BCL10 Monoclonal Antibody (OTI4A8), TrueMAB
BCL10 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, ICC/IF, Flow cytometry에 적합합니다. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인간 BCL10 full-length 단백질을 면역원으로 제작되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A8 |
| Immunogen | Full length human recombinant protein of human BCL10 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein involved in the adaptive immune response.
It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-κB via NIK and IKK.
BCL-10 acts as an adapter between the upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex.
It is a substrate for MALT1, and mutations in this gene can lead to Immunodeficiency 37 or mucosa-associated lymphoid type lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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