Thermo Fisher Scientific TRIP11/TRIP230 Polyclonal Antibody
TRIP11/TRIP230 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합. 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- A301187Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIP11/TRIP230 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of Human thyroid hormone receptor interactor 11 (thyroid hormone receptor interactor, 230 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa.
It is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities.
Trip230 interacts with Rb and thyroid hormone receptor (TR) through distinct domains:
- Complex formation with Rb occurs in a hormone-independent manner.
- Complex formation with TR occurs in a thyroid hormone-dependent manner.
After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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