
Thermo Fisher Scientific TRIP11/TRIP230 Polyclonal Antibody
TRIP11/TRIP230 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인체 반응성, 비결합형 액상 형태로 연구용에 최적화.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of Human thyroid hormone receptor interactor 11 (thyroid hormone receptor interactor, 230 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa.
The gene is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities.
Trip230 interacts with Rb and thyroid hormone receptor (TR) via two distinct domains:
- Complex formation with Rb is hormone-independent.
- Complex formation with TR is thyroid hormone-dependent.
After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: A301-187A_TRIP230_Q15643-1_Rabbit.svg, A301-187A_TRIP230_Q15643-1_Rabbit_PDP.jpeg)
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