Thermo Fisher Scientific RAMP2 (extracellular) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:200

Flow Cytometry (Flow)

• Tested Dilution: 5 µg/0.5×10^6 cells

Product Specifications

Product Specific Information

• Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size
• Ships as lyophilized powder at room temperature
• Store at -20°C upon arrival
• Reconstituted solution stable at 4°C for up to 1 week
• For longer storage, aliquot and keep at -20°C
• Avoid multiple freeze/thaw cycles
• Centrifuge antibody preparations before use (10,000 × g, 5 min)

Target Information

The RAMP2 protein is a member of the receptor (calcitonin) activity modifying protein family (RAMPs), which are single-transmembrane-domain proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required for transporting calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor depending on the expressed RAMP family member. In the presence of RAMP2, CRLR functions as an adrenomedullin receptor. RAMP2 is involved in core glycosylation and transportation of the adrenomedullin receptor to the cell surface.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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