Thermo Fisher Scientific METTL7A Monoclonal Antibody (OTI4B10), TrueMAB
METTL7A 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P) 검증 완료. Human 및 Rat 시료에 반응. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 34–104 of human METTL7A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MettL7A belongs to the methyltransferase superfamily and is a probable methyltransferase. Methyltransferases transfer a methyl group from a donor to an acceptor, commonly occurring on nucleic bases in DNA or amino acids in proteins.
DNA methylation is essential for gene regulation and normal embryonic growth in mammals. Disruption of methyltransferase genes can lead to lethal phenotypes. Aberrant methylation of tumor suppressor genes has been linked to tumorigenesis and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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