Thermo Fisher Scientific Sarcomeric Actinin Alpha 2/ACTN2 Recombinant Rabbit Monoclonal Antibody (ACTN2/7041R)
Recombinant rabbit monoclonal antibody targeting human ACTN2 for IHC and peptide array applications. High specificity and reproducibility. Supplied as a liquid, unconjugated format, 200 µg/mL concentration. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ACTN2/7041R |
| Immunogen | Recombinant fragment (aa 557–692) of human ACTN2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alpha actinins belong to the spectrin gene superfamily, a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in various cell types. In nonmuscle cells, it is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane. In skeletal, cardiac, and smooth muscle cells, alpha actinin localizes to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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