Thermo Fisher Scientific BMP-4 Polyclonal Antibody
BMP-4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 보존됩니다. Human에 반응하며 다양한 종에 예측 반응성을 가집니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–287 of Human BMP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.34 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544764 |
Product Specific Information
- Recommended positive controls: HepG2 conditioned medium, NIH-3T3, JC
- Predicted reactivity: Mouse (97%), Rat (96%), Dog (97%), Pig (98%), Rabbit (96%), Sheep (98%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family, which belongs to the transforming growth factor-beta (TGF-β) superfamily. These proteins are involved in growth and differentiation processes. BMPs were first identified by their ability to induce endochondral osteogenesis in vivo. BMP4 plays a crucial role in the initiation of endochondral bone formation in humans, and reduced expression has been linked to bone-related disorders such as Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5′ untranslated region has been reported, producing three transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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