Thermo Fisher Scientific Thymidine Phosphorylase Polyclonal Antibody
Thymidine Phosphorylase 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용 가능. Human 반응성 및 Mouse 예측 반응성 85%. 항원 친화 크로마토그래피로 정제된 액상 형태, 장기보관 시 -20°C 권장.
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Thermo Fisher Scientific Thymidine Phosphorylase Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–338 of Human PD-ECGF (Thymidine Phosphorylase, UniProt ID: P19971-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544767 |
Product Specific Information
- Recommended positive controls: NCI-H929
- Predicted reactivity: Mouse (85%), Rat (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Thymidine Phosphorylase (PD-ECGF), also known as gliostatin, is a platelet-derived endothelial growth factor. In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine into their corresponding bases and 2-deoxyribose-1-phosphate.
This protein is chemotactic and mitogenic for endothelial cells, acts as a non-heparin binding angiogenic factor present in platelets, and plays a role in the activation of fluoropyrimidines—cytotoxic agents used in cancer treatment.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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