Thermo Fisher Scientific FOXB1/FOXB2 Polyclonal Antibody
FOXB1/FOXB2 단백질을 인식하는 Rabbit Polyclonal Antibody로 WB 및 IHC(P) 실험에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. 장기 보관 시 -20°C에서 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 40–87 of Human FoxB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718987 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins involved in transcriptional regulation and may be associated with various cancers.
FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family, each containing one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus and function as transcription factors binding to DNA via their forkhead domains.
In mice, defects in the FOXB1 gene are associated with retarded development of the central nervous system (CNS), suggesting a role in CNS organization and function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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