Thermo Fisher Scientific TGR5 Polyclonal Antibody
Human TGR5 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human TGR5. Recombinant protein control fragment (Product #RP-101990). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856967 |
Product Specific Information
Immunogen sequence: LGDQRYTAPW RAAAQRCLQG LWGRASRD
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activation of MAP kinase signaling, and receptor internalization. The receptor is involved in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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