Thermo Fisher Scientific CD45RB Recombinant Rabbit Monoclonal Antibody (PTPRC, 1783R)
Thermo Fisher Scientific의 CD45RB Recombinant Rabbit Monoclonal Antibody는 인간 CD45RB 단백질을 표적으로 하는 고품질 항체입니다. Western blot, IHC, ICC/IF, Flow cytometry 등에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- 5788-RBM23-P1ABX
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PTPRC, 1783R |
| Immunogen | Recombinant human full-length CD45RB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry on PFA-fixed tissues: incubate antibody for 30 minutes at room temperature.
- Formalin-fixed tissues require heating sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD45RB is a receptor-type protein tyrosine phosphatase and a CD45 glycoprotein isoform.
CD45 plays a crucial role in lymphocyte development and antigen signaling by regulating Src-family kinases. It promotes cell survival through integrin-mediated signal transduction and participates in DNA fragmentation during apoptosis.
Different CD45 isoforms vary in extracellular domains and expression patterns depending on cell type and physiological state. CD45RB is expressed in microglia and inflammatory cells.
CD45 is expressed on cells of the human hematopoietic lineage, excluding mature red blood cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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