Thermo Fisher Scientific CNTF Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitution:
Reconstitute with 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freeze-thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

The CNTF (Ciliary Neurotrophic Factor) protein is a polypeptide hormone acting mainly in the nervous system.
It promotes neurotransmitter synthesis and neurite outgrowth in specific neuronal populations and serves as a potent survival factor for neurons and oligodendrocytes.
It may help reduce tissue destruction during inflammatory attacks.
Mutations causing aberrant splicing can lead to CNTF deficiency, though not directly linked to neurological disease.
A read-through transcript variant composed of ZFP91 and CNTF sequences has been identified, considered non-coding.
Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.