Thermo Fisher Scientific FOXP1 Monoclonal Antibody (JC12)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

JC12

Immunogen

Proprietary Immunogen.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4°C or -20°C if preferred

Shipping conditions

Wet ice

RRID

AB_2106982

Product Specific Information

A suggested positive control for immunohistochemical applications for this product is human tonsil. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. 1mM EDTA, pH 8.0, is recommended for this purpose.

Mouse anti FOXP1 antibody, clone JC12 recognizes human FOXP1, also known as Forkhead box protein P1, Mac-1-regulated forkhead or MFH.

Target Information

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.