Thermo Fisher Scientific SAPK4 Polyclonal Antibody
Thermo Fisher Scientific의 SAPK4 Polyclonal Antibody는 인간 p38 MAPK13(delta)을 인식하는 토끼 유래 IgG 항체로, WB 및 ICC/IF에 적합합니다. 고순도의 항원 친화 크로마토그래피로 정제되었으며, 다양한 종(원숭이, 소, 고양이)에서도 반응이 예상됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to human p38 MAPK13 delta (aa316–333 and aa113–126) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2662066 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Cat.
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by phosphorylation through MAP kinase kinases or autophosphorylation via interaction with MAP3K7IP1/TAB1. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct SAPK4 isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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