
Thermo Fisher Scientific CD34 Monoclonal Antibody (QBEND/10), FITC
인간 CD34 항원을 인식하는 Mouse Monoclonal Antibody (Clone QBEND/10)로, FITC 형광 표지되어 Flow Cytometry 및 IHC에 적합. Cynomolgus monkey 및 Human 반응성. 4°C 암소 보관, FACS용 100 tests/1 mL 제공.
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Thermo Fisher Scientific CD34 Monoclonal Antibody (QBEND/10), FITC
Applications
- Immunohistochemistry (IHC)
Tested dilution: Not specified
View 21 publications - Flow Cytometry (Flow)
Tested dilution: Neat–1:10
View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human |
| Published Species | Human, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | QBEND/10 |
| Immunogen | Human endothelial cell membrane vesicles |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538402 |
Additional Formats
Product Specific Information
- Does not react with bovine, dog, rat, or sheep.
- For FACS analysis: use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
- Mouse anti-Human CD34 antibody (clone QBEND/10) recognizes human CD34 antigen, also known as Hematopoietic progenitor cell antigen CD34.
- Quantity: 100 Tests / 1 mL.
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) found on various stem cell populations. It serves as a stem cell marker with reversible expression on human hematopoietic stem cells. CD34 may function as a surface receptor mediating endocytosis and regulating adhesion, differentiation, and proliferation of hematopoietic and progenitor cells. It likely plays a role in stem cell attachment to bone marrow extracellular matrix or stromal cells and may act as a scaffold for glycans enabling lectin interactions. The intracellular domain is phosphorylated by protein kinase C, suggesting involvement in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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