Thermo Fisher Scientific NK1.1 Monoclonal Antibody (PK136)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5-10 µg/mL

View 19 publications 19 publications

Immunoprecipitation (IP)

Assay-dependent

-

ChIP assay (ChIP)

-

View 1 publication 1 publication

Functional Assay (Functional)

Assay-dependent

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

PK136

Immunogen

Spleen and bone marrow cells from CE mice if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NK1.1,uniProtId:P27814-1,ncbiNodeId:10090,antigenRange:1-223,antigenLength:223,antigenImageFileName:MA5-16916_NK1.1_P27814-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16916_NK1.1_P27814-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:NK1.1,uniProtId:P27812-1,ncbiNodeId:10090,antigenRange:1-223,antigenLength:223,antigenImageFileName:MA5-16916_NK1.1_P27812-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16916_NK1.1_P27812-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538393

Product Specific Information

This antibody does not react with human or rat.

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti Mouse CD161 / NK1.1 antibody, clone PK136 recognizes the mouse NK1.1 cell surface antigen, a cell surface glycoprotein encoded by members of the NKR-P1 gene family.

Target Information

NK1.1 (Killer cell lectin-like receptor subfamily B, member 1, KLRB1, NKR-P1A, CD161, cluster of differentiation 161), refers to Natural Killer (NK) cells, lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus. NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.