Thermo Fisher Scientific Syntaxin 4 Polyclonal Antibody
Syntaxin 4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 세포막 단백질 STX4 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human STX4. Recombinant protein control fragment (Product #RP-95939). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648059 |
Product Specific Information
Immunogen sequence:
MRDRTHELRQ GDDSSDEEDK ERVALVVHPG TARLGSPDEE FFHKVRTIRQ TIVKLGNKVQ ELEKQQVTIL ATPLPEESMK QELQNLRDEI KQLGREIRLQ LKAIEPQKEE ADENYNSVNT RMRKTQHGVL SQQFVELINK CNSMQSE
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 86%
Target Information
STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.
It is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane.
Together with STXB3 and VAMP2, STX4 may play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
STX4 may also be involved in docking of synaptic vesicles at presynaptic active zones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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