Thermo Fisher Scientific PRICKLE1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRICKLE1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRICKLE1,uniProtId:Q96MT3-1,ncbiNodeId:9606,antigenRange:505-647,antigenLength:831,antigenImageFileName:PA5-51570_PRICKLE1_Q96MT3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51570_PRICKLE1_Q96MT3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645937

Product Specific Information

Immunogen sequence: GASGYNHDET QWYEDSLECL SDLKPEQSVR DSMDSLALSN ITGASVDGEN KPRPSLYSLQ NFEEMETEDC EKMSNMGTLN SSMLHRSAES LKSLSSELCP EKILPEEKPV HLPVLRRSKS QSRPQQVKFS DDVIDNGNYD IEI

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 94%.

Target Information

Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.