Thermo Fisher Scientific DBI Polyclonal Antibody, MaxPab
DBI 단백질을 타겟으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot에 사용 가능하며, 인간 DBI 단백질에 반응합니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DBI (NP_065438.1, 1 a.a. ~104 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK QATVGDINTE RPGMLDFTGK AKWDAWNELK GTSKEDAMKA YINKVEELKK KYGI
Target Information
This gene encodes diazepam binding inhibitor (DBI), a protein regulated by hormones and involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines. These compounds modulate signal transduction at type A gamma-aminobutyric acid receptors in brain synapses.
The protein is conserved from yeast to mammals, with a highly conserved hydrophobic binding domain for medium- and long-chain acyl-CoA esters. DBI also mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin, and plays a role in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes are located on chromosomes 6, 8, and 16. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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