Thermo Fisher Scientific ZCCHC6 Polyclonal Antibody
ZCCHC6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간 시료에 반응하며, 4°C에서 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 to 125 of Human Terminal uridylyltransferase 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, facilitating global mRNA decay. Essential for oocyte maturation and fertility. Involved in microRNA-induced gene silencing and regulation of microRNA biogenesis through multiple uridylation mechanisms. Functions as a suppressor of miRNA biogenesis by mediating terminal uridylation of pre-let-7 RNA, preventing Dicer processing and promoting degradation. Works redundantly with TUT4 to regulate transcript stability and restrict retrotransposition of LINE-1 elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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