Thermo Fisher Scientific DMGDH Polyclonal Antibody
Rabbit polyclonal antibody targeting human DMGDH for Western blot applications. Detects endogenous DMGDH protein. Affinity-purified, liquid form, unconjugated, stored in PBS with glycerol. Suitable for research use in studying choline catabolism and mi...
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Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from C-terminal of human DMGDH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635474 |
Product Specific Information
The antibody detects endogenous levels of total DMGDH protein.
Target Information
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is a monomer located in the mitochondrial matrix and uses flavin adenine dinucleotide and folate as cofactors. Mutations in this gene can cause dimethylglycine dehydrogenase deficiency, characterized by fishlike body odor, chronic muscle fatigue, and elevated serum creatine kinase (muscle form). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-50021_DMGDH_Q9UI17-1_Rabbit.svg, PA5-50021_DMGDH_Q9UI17-1_Rabbit_PDP.jpeg)
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