Thermo Fisher Scientific GNB3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GNB3 (aa 2–50). Suitable for WB and IHC applications. Lyophilized form with optional glycerol stabilization. Store at 4°C short term or -20°C long term. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 2–50 of human GNB3 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10709567 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 100 µL of sterile water.
- The peptide is homologous in rat and mouse.
Target Information
Heterotrimeric guanine nucleotide-binding proteins encoded by this gene are associated with essential hypertension and obesity. The polymorphism in this gene is linked to the occurrence of the splice variant GNB3-s, which shows increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside the splice donor and acceptor sites. Additional splice variants may exist but have not been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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