Thermo Fisher Scientific GBB1 Polyclonal Antibody
Thermo Fisher Scientific의 GBB1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 토끼 유래 다클론 항체입니다. Western blot과 IHC에 적합하며, 내부 영역 합성 펩타이드로 제작되었습니다. 동결건조 형태로 제공되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of human GBB1 (Transducin beta chain 1, GNB1, Guanine nucleotide binding protein subunit beta-1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in many species including rat, mouse, zebrafish, and xenopus.
- Specificity: GBB1.
Target Information
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process begins when rhodopsin absorbs light within the retina, activating transducin, a GTP-binding protein. Activated transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE), leading to closure of ion channels and signal transmission. Rhodopsin activity is terminated by phosphorylation and arrestin binding.
Rod and cone cells differ in transducin subunit composition, which contributes to their varying light sensitivities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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