
Thermo Fisher Scientific EPM2A Polyclonal Antibody, Biotin
Biotin 결합된 EPM2A 폴리클로날 항체로 Western blot 및 IHC에 사용 가능. 인간 시료 반응성, Goat/IgG 유래. 고순도 액상 형태로 TBS 버퍼에 BSA 함유. EPM2A isoform a 인식, 연구용 전용 제품.
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Thermo Fisher Scientific EPM2A Polyclonal Antibody, Biotin
Applications and Tested Dilution
- Western Blot (WB): 1–3 µg/mL
- Immunohistochemistry (IHC): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EATGHTNEMKHTTD |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2933020 |
Product Specific Information
- This antibody is expected to recognize isoform a (NP_005661.1) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with proteins involved in glycogen metabolism and exhibits phosphatase activity against phosphorylated complex carbohydrates, suggesting a role in glycogen metabolism regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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