Thermo Fisher Scientific ACVR1 Polyclonal Antibody
인간 ACVR1 단백질을 인식하는 토끼 폴리클로날 항체로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 용액 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ACVR1. Recombinant protein control fragment (Product # RP-108372) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856643 |
Product Specific Information
Immunogen sequence:
EKPKVNPKLY MCVCEGLSCG NEDHCEGQQC FSSLSINDGF HVYQKGCFQV YEQGKMTCKT PPSPGQAVEC CQGDWCNRNI TAQLPTKGKS FPGTQNFHLE
Target Information
Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.
ACVR1 signals a specific transcriptional response in concert with activin type II receptors.
The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors.
Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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