Thermo Fisher Scientific UHRF1 Monoclonal Antibody (2A11)
UHRF1 단백질을 검출하기 위한 Thermo Fisher Scientific의 단일클론 항체(2A11). Western blot 및 면역세포화학(ICC/IF)에 적합. 인간 및 생쥐 반응성, 고순도(>95%) 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A11 |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human UHRF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717303 |
Product Specific Information
The antibody was affinity-purified from mouse ascites by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases.
The protein binds to specific DNA sequences and recruits a histone deacetylase to regulate gene expression.
Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle.
It plays a major role in the G1/S transition by regulating topoisomerase IIα and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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