Thermo Fisher Scientific GTF2B Monoclonal Antibody (3H2)
GTF2B 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되어 순도 >95%. PBS/glycerol 버퍼에 보존되며 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H2 |
| Immunogen | Recombinant full-length Human GTF2B (UniProt ID: Q00403-1, antigen range: 1–316, antigen length: 316) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717302 |
Product Specific Information
The antibody was affinity-purified from mouse ascites by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Ubiquitin is a 76 amino acid, highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. This process regulates the concentrations of key regulatory proteins by limiting their lifespans. Polyubiquitination is a common modification involving activation, conjugation, and ligation steps mediated by E1, E2, and E3 enzymes. Deubiquitination enzymes reverse this marking. Ubiquitin-mediated tagging is involved in numerous cellular processes including cell cycle, differentiation, apoptosis, signal transduction, DNA repair, transcription regulation, transport, stress responses, immune responses, and nervous system functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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