Thermo Scientific™

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Cells

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells contain the human Dopamine Receptor 2 (D2)자세히 알아보기

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells contain the human Dopamine Receptor 2 (D2) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cells (Cat. No. K1536) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Chimeric G protein, Gqo5.

The GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells are functionally validated for Z` and EC50 concentrations of apomorphine. In addition, GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The D2 receptor is found primarily in the brain. There are two forms of D2 which are created by alternate splicing: a short form and a long form. This assay uses the long form, although little difference in ligand binding or signaling has been seen between the two forms.

사양

등록 번호NM_000795

어세이 입력Cell-based beta lactamase reporter gene

셀 상태Dividing Cells

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호D2

개체군 상태Single Cell Clone Origin

제품라인GeneBLAzer™

수량2 x 106 Cells

리포터 유전자BLA (Beta-Lactamase)

타겟 입력DRD2, D2

유형CHO-K1 Cells

세포주CHO-K1

System TypeGeneBLAzer™

Druggable TargetGPCR

Unit SizeEach