Thermo Scientific™

GeneBLAzer™ D1-CRE-bla CHO-K1 Cells

GeneBLAzer™ D1-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 1 (D1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.자세히 알아보기

GeneBLAzer™ D1-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 1 (D1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ D1-CRE-bla CHO-K1cells are functionally validated for Z` and EC50 concentrations of dihydrexidine. In addition, GeneBLAzer™ D1-CRE-bla CHO-K1 DA cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

Agonists and antagonists of dopamine D1 receptors are in various stages of clinical trials for the treatment of neurological disorders like Parkinsons disease, Alzheimers disease, schizophrenia, and psychosis.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

사양

어세이 입력Cell-based beta lactamase reporter gene

셀 상태Dividing Cells

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호DRD1

제품라인GeneBLAzer™

수량2 x 106 Cells

리포터 유전자BLA (Beta-Lactamase)

타겟 입력DRD1, D1

유형CHO-K1 Cells

세포주CHO-K1

System TypeGeneBLAzer™

Druggable TargetGPCR

Unit SizeEach