Thermo Fisher Scientific CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 600, eBioscience
Mouse CD41a 단백질을 인식하는 eBioMWReg30 단클론 항체로, Super Bright 600 형광체 결합형입니다. Flow cytometry에 최적화되어 있으며, 혈소판 및 조혈 줄기세포 연구에 적합합니다. 405 nm excitation/600 nm emission 특성을 가지며, 빛에 민감해 암조건 보관이 필요합니다.
- 카탈로그번호
- 63-0411-82
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 600, eBioscience
Thermo Fisher Scientific CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 600, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | 1.0 µg/test | View 7 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rat / IgG1, kappa |
| Recommended Isotype Control | Rat IgG1 kappa Isotype Control (eBRG1), Super Bright™ 600 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioMWReg30 (MWReg30) |
| Conjugate | Super Bright™ 600 |
| Excitation / Emission Max | 414 / 601 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784855 |
Available Formats
- Unconjugated
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- eFluor 450
- FITC
- Functional Grade
- NovaFluor Blue 510
- NovaFluor Blue 555
- NovaFluor Blue 660-120S
- NovaFluor Yellow 570
- NovaFluor Yellow 660
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 645
- Request custom conjugation
Product Specific Information
The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). Initially known to be expressed on platelets and megakaryocytes, CD41 is also found on hematopoietic progenitors in embryos, fetuses, and adults. CD41 forms a receptor with CD61 (gpIIIa, integrin beta III) that mediates platelet adhesion through fibrinogen, fibronectin, and vitronectin binding.
CD150+CD48−CD41− expression efficiently identifies hematopoietic stem cells (HSCs) with enhanced reconstitution potential.
Reported application: flow cytometric analysis.
Tested application: flow cytometric analysis of mouse platelets using ≤1.0 µg/test (100 µL final volume, 10⁵–10⁸ cells/test). Optimize antibody titration per assay.
Super Bright 600 is a tandem dye excited by the violet laser (405 nm) and emits at 600 nm; recommended filter: 610/20 bandpass.
Use Super Bright Complete Staining Buffer (Product # SB-4401) when staining with multiple Super Bright conjugates to minimize polymer interactions.
Light sensitive—protect from exposure.
Samples may be fixed using IC Fixation Buffer (Product # 00-8222-49) or 1-step Fix/Lyse Solution (Product # 00-5333-57) for up to 3 days at 4°C in the dark with minimal brightness loss.
Excitation: 405 nm
Emission: 600 nm
Laser: Violet Laser
Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) consists of two subunits (120 kDa alpha and 23 kDa beta) that interact with CD61 in the presence of calcium to form a functional adhesive receptor. CD41 mediates platelet aggregation and binds von Willebrand factor, fibrinogen, fibronectin, and vitronectin during vessel injury. Expressed mainly in megakaryocyte-platelet lineages and early hematopoietic differentiation stages.
Associated diseases include Glansmann Thrombasthenia and Platelet-type 16 bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.