Thermo Fisher Scientific NR5A1 Recombinant Rabbit Monoclonal Antibody (ARC2457)
NR5A1(SF-1)을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체로, Western blot 및 ELISA에 적합. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2457 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 351–461 of human Steroidogenic factor-1 (SF-1/NR5A1) (Q13285) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897824 |
Product Specific Information
- Positive Samples: BxPC-3, Mouse ovary, Mouse spleen
- Immunogen sequence:
AQELVLQLLA LQLDRQEFVC LKFIILFSLD LKFLNNHILV KDAQEKANAA LLDYTLCHYP HCGDKFQQLL LCLVEVRALS MQAKEYLYHK HLGNEMPRNN LLIEMLQAKQ T
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system.
SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland, and promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
It contains two activation function domains (AF1 and AF2) necessary for interaction with other nuclear receptors and coactivators/corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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